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Dogs and Cats. DES is used primarily to treat urinary incontinence in spayed females. Estrogens increase urethral tone and help to prevent leaking or dribbling of urine. DES usually is effective。

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Diethylstilbestrol (DES) has only one primary use: treating sphincter tone incontinence in female dogs. DES is used at extremely low doses to avoid the toxicity issues that have been a。

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